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Loss of Pten promotes angiogenesis and enhanced vegfaa expression in zebrafish

SUMMARY Angiogenesis, the emergence of vessels from an existing vascular network, is pathologically associated with tumor progression and is of great interest for therapeutic intervention. PTEN is a frequently mutated tumor suppressor and has been linked to the progression of many types of tumors, i...

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Autori principali: Suma Choorapoikayil, Bart Weijts, Rianne Kers, Alain de Bruin, Jeroen den Hertog
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Company of Biologists 2013-09-01
Serie:Disease Models & Mechanisms
Accesso online:http://dmm.biologists.org/content/6/5/1159
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