Another one bites the dust; ARTS enables degradation of Bcl-2 by XIAP
ARTS (Sept4_i2) is a pro-apoptotic mitochondrial tumor suppressor protein which binds to and causes degradation of XIAP (X-linked inhibitor of apoptosis). We recently showed that ARTS brings XIAP into close proximity to Bcl-2, creating a complex which enables degradation of both these major anti-apo...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis Group
2018-07-01
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| Col·lecció: | Molecular & Cellular Oncology |
| Matèries: | |
| Accés en línia: | http://dx.doi.org/10.1080/23723556.2018.1441630 |
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