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Another one bites the dust; ARTS enables degradation of Bcl-2 by XIAP

ARTS (Sept4_i2) is a pro-apoptotic mitochondrial tumor suppressor protein which binds to and causes degradation of XIAP (X-linked inhibitor of apoptosis). We recently showed that ARTS brings XIAP into close proximity to Bcl-2, creating a complex which enables degradation of both these major anti-apo...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Dana Mamriev, Sarit Larisch
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Taylor & Francis Group 2018-07-01
Sarja:Molecular & Cellular Oncology
Aiheet:
Linkit:http://dx.doi.org/10.1080/23723556.2018.1441630
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