Donor telomeres and their magnitude of shortening post-allogeneic haematopoietic cell transplant impact survival for patients with early-stage leukaemia or myelodysplastic syndromeResearch in context

Summary: Background: Donor selection is a key success factor in allogeneic haematopoietic cell transplant (HCT). We evaluated the potential impact of donor leucocyte telomere length (LTL) and LTL shortening in recipients at three-month post-HCT (LTL-3MS) on the two-year HCT outcomes. Methods: We id...

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Detalhes bibliográficos

Principais autores:	Shahinaz M. Gadalla, Hormuzd A. Katki, Tsung-Po Lai, Paul L. Auer, Casey L. Dagnall, Caitrin Bupp, Amy A. Hutchinson, James J. Anderson, Kyra J.W. Mendez, Stephen R. Spellman, Valerie Stewart, Sharon A. Savage, Stephanie J. Lee, John E. Levine, Wael Saber, Abraham Aviv
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2025-04-01
coleção:	EBioMedicine
Assuntos:	Telomeres Telomere length Haematopoietic cell transplant Donor selection Relapse
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2352396425000854
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