Donor telomeres and their magnitude of shortening post-allogeneic haematopoietic cell transplant impact survival for patients with early-stage leukaemia or myelodysplastic syndromeResearch in context

Summary: Background: Donor selection is a key success factor in allogeneic haematopoietic cell transplant (HCT). We evaluated the potential impact of donor leucocyte telomere length (LTL) and LTL shortening in recipients at three-month post-HCT (LTL-3MS) on the two-year HCT outcomes. Methods: We id...

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Autors principals:	Shahinaz M. Gadalla, Hormuzd A. Katki, Tsung-Po Lai, Paul L. Auer, Casey L. Dagnall, Caitrin Bupp, Amy A. Hutchinson, James J. Anderson, Kyra J.W. Mendez, Stephen R. Spellman, Valerie Stewart, Sharon A. Savage, Stephanie J. Lee, John E. Levine, Wael Saber, Abraham Aviv
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2025-04-01
Col·lecció:	EBioMedicine
Matèries:	Telomeres Telomere length Haematopoietic cell transplant Donor selection Relapse
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S2352396425000854
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