Single-cell RNA sequencing reveals cellular and molecular heterogeneity in extensive-stage small cell lung cancer with different chemotherapy responses

Abstract Despite its rapid growth and early metastasis, small cell lung cancer (SCLC) is more chemosensitive than other lung cancers. However, some patients with extensive-stage SCLC (ES-SCLC) do not respond to first-line chemotherapy, resulting in poorer prognoses due to inter- and intratumoral het...

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Autors principals:	Zhan Gu, Yongqing Heng, Rui Fan, Jie Luo, Lixia Ju
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2025-04-01
Col·lecció:	Cancer Cell International
Matèries:	Small cell lung cancer Chemotherapy Single-cell Tumor microenvironment
Accés en línia:	https://doi.org/10.1186/s12935-025-03785-z
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