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Single-cell RNA sequencing reveals cellular and molecular heterogeneity in extensive-stage small cell lung cancer with different chemotherapy responses

Abstract Despite its rapid growth and early metastasis, small cell lung cancer (SCLC) is more chemosensitive than other lung cancers. However, some patients with extensive-stage SCLC (ES-SCLC) do not respond to first-line chemotherapy, resulting in poorer prognoses due to inter- and intratumoral het...

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Principais autores: Zhan Gu, Yongqing Heng, Rui Fan, Jie Luo, Lixia Ju
פורמט: Artigo
שפה:Inglês
יצא לאור: BMC 2025-04-01
סדרה:Cancer Cell International
נושאים:
Small cell lung cancer
Chemotherapy
Single-cell
Tumor microenvironment
גישה מקוונת:https://doi.org/10.1186/s12935-025-03785-z
תגים: הוספת תג
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