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Association between acquired uniparental disomy and homozygous mutations and HER2/ER/PR status in breast cancer.

<h4>Background</h4>Genetic alterations in cellular signaling networks are a hallmark of cancer, however, effective methods to discover them are lacking. A novel form of abnormality called acquired uniparental disomy (aUPD) was recently found to pinpoint the region of mutated genes in various cancers...

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Autors principals: Musaffe Tuna, Marcel Smid, Dakai Zhu, John W M Martens, Christopher I Amos
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2010-11-01
Col·lecció:PLoS ONE
Accés en línia:https://doi.org/10.1371/journal.pone.0015094
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