The effect of amyloid on microglia-neuron interactions before plaque onset occurs independently of TREM2 in a mouse model of Alzheimer's disease
Genetic studies identified mutations in several immune-related genes that confer increased risk for developing Alzheimer's disease (AD), suggesting a key role for microglia in AD pathology. Microglia are recruited to and actively modulate the local toxicity of amyloid plaques in models of AD through...
Збережено в:
| Автори: | , , |
|---|---|
| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
Elsevier
2020-11-01
|
| Серія: | Neurobiology of Disease |
| Предмети: | |
| Онлайн доступ: | http://www.sciencedirect.com/science/article/pii/S0969996120303478 |
| Теги: |
Немає тегів, Будьте першим, хто поставить тег для цього запису!
|