Dysferlin stabilizes membrane nanodomains of cardiomyocytes after myocardial infarction

Abstract Despite advances in acute care medicine, myocardial infarction (MI) remains a predominant cause of premature death and heart failure. In the MI border zone, cardiomyocytes are exposed to high biomechanical stress that impairs the integrity of the sarcolemmal membrane. Hence, we hypothesized...

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Autors principals:	Justus B. Wegener, Yannik Zühlke, Carolin Fleischhacker, Justus Marks, Brian Foo, Niklas Bader, Gabriel C. Riedemann, Jasper Wedemeyer, Kim-Chi Vu, Ana M. Vergel Leon, Nora Josefine Paulke, Tobias Kohl, Henning Urlaub, Constanze Schmidt, Gerd Hasenfuß, Tobias Moser, Eva A. Rog-Zielinska, Christof Lenz, Stephan E. Lehnart, Sören Brandenburg
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2026-03-01
Col·lecció:	Scientific Reports
Matèries:	Dysferlin Cardiomyocytes Membrane repair Myocardial infarction Proteomics
Accés en línia:	https://doi.org/10.1038/s41598-026-42800-9
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