Pilot investigations into the mechanistic basis for adverse effects of glucocorticoids in dysferlinopathy

Abstract Background Dysferlinopathies are a clinically heterogeneous group of muscular dystrophies caused by gene mutations resulting in deficiency of the membrane-associated protein dysferlin. They manifest post-growth and are characterised by muscle wasting (primarily in the limb and limb-gridle m...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Erin M. Lloyd, Rachael C. Crew, Vanessa R. Haynes, Robert B. White, Peter J. Mark, Connie Jackaman, John M. Papadimitriou, Gavin J. Pinniger, Robyn M. Murphy, Matthew J. Watt, Miranda D. Grounds
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2024-08-01
Schriftenreihe:	Skeletal Muscle
Schlagworte:	Limb-girdle muscular dystrophy Dysferlinopathy Dysferlin Glucocorticoids Dexamethasone Skeletal muscle
Online-Zugang:	https://doi.org/10.1186/s13395-024-00350-6
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