Upregulation of Chemoresistance by Mg²⁺ Deficiency through Elevation of ATP Binding Cassette Subfamily B Member 1 Expression in Human Lung Adenocarcinoma A549 Cells

Several anticancer drugs including cisplatin (CDDP) induce hypomagnesemia. However, it remains fully uncertain whether Mg²⁺ deficiency affects chemosensitivity of cancer cells. Here, we investigated the effect of low Mg²⁺ concentration (LM) on proliferation and chemosensitivity...

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Autors principals:	Saki Onuma, Aya Manabe, Yuta Yoshino, Toshiyuki Matsunaga, Tomohiro Asai, Akira Ikari
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2021-05-01
Col·lecció:	Cells
Matèries:	lung adenocarcinoma chemoresistance ABCB1 hypomagnesemia
Accés en línia:	https://www.mdpi.com/2073-4409/10/5/1179
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