An mRNA Vaccine Based on Antigens From Conserved Regions of Monkeypox Virus A35R and M1R With a Dimer‐Like Conformation Confers Protection Against Both Monkeypox Virus and Vaccinia Virus Infections in Mice

ABSTRACT The 2022 global mpox outbreak caused by the monkeypox virus (MPXV) has underscored the urgent need for improved vaccine development. To address this need, we developed four candidate vaccine antigens based on conserved sequences of the MPXV A35R and M1R proteins utilizing a lipid nanopartic...

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Bibliografiska uppgifter

Huvudupphov:	Cong Tang, Longhai Yuan, Yun Xie, Yun Yang, Yanan Zhou, Junbing Wang, Hao Yang, Rui Peng, Jiali Xu, Wenhai Yu, Qing Huang, Wenqi Quan, Baisheng Li, Youchun Wang, Shuaiyao Lu
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	Wiley 2026-02-01
Serie:	MedComm
Ämnen:	mRNA vaccine monkeypox virus (MPXV) vaccinia virus (VACV) vaccine antigen design
Länkar:	https://doi.org/10.1002/mco2.70614
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