Protective efficacy of a genetically modified attenuated vaccinia virus Tiantan strain against monkeypox virus challenge in a small animal model

ABSTRACT Vaccinia virus (VACV) confers cross-protective immunity against monkeypox virus (MPXV), the causative agent of mpox, and has therefore been extensively exploited as a preventive vaccine. VACV Tiantan strain (VTT) is a second-generation smallpox vaccine used in China in the last century, and...

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Päätekijät:	Wenhao Su, Tingting Zhao, Xiuxiu Ren, Shishi Li, Qiufang Huang, Jingjing Liu, Xiaohuan Zhang, Zihao Ge, Jiangbo Wei
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	American Society for Microbiology 2026-02-01
Sarja:	Journal of Virology
Aiheet:	monkeypox virus monkeypox vaccine vaccinia virus Tiantan strain attenuated vaccinia virus virulence
Linkit:	https://journals.asm.org/doi/10.1128/jvi.01843-25
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