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Functional characterisation of the WW minimal domain for delivering therapeutic proteins by adenovirus dodecahedron.

Protein transduction offers a great therapeutic potential by efficient delivery of biologically active cargo into cells. The Adenovirus Dd (Dodecahedron) has recently been shown to deliver proteins fused to the tandem WW(2-3-4) structural domains from the E3 ubiquitin ligase Nedd4. In this study, we...

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Autors principals: Ana Villegas-Méndez, Pascal Fender, Marina I Garin, Romy Rothe, Lavinia Liguori, Bruno Marques, Jean-Luc Lenormand
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2012-01-01
Col·lecció:PLoS ONE
Accés en línia:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23028993/pdf/?tool=EBI
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