Evaluation of the human type 3 adenoviral dodecahedron as a vector to target acute myeloid leukemia

Intensive systemic chemotherapy is the gold standard of acute myeloid leukemia (AML) treatment and is associated with considerable off-target toxicities. Safer and targeted delivery systems are thus urgently needed. In this study, we evaluated a virus-like particle derived from the human type 3 aden...

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Bibliographic Details

Main Authors:	Benjamin Caulier, Gaëlle Stofleth, Dalil Hannani, Mélanie Guidetti, Véronique Josserand, David Laurin, Jadwiga Chroboczek, Pascal Mossuz, Dominique Plantaz
Format:	Artigo
Language:	Inglês
Published:	Elsevier 2021-03-01
Series:	Molecular Therapy: Methods & Clinical Development
Subjects:	adenoviral dodecahedron virus-like particles acute myeloid leukemia leukemic stem cells delivery vector
Online Access:	http://www.sciencedirect.com/science/article/pii/S2329050120302369
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