Impact of Oxygen Availability on the Organelle‐Specific Redox Potentials and Stress in Recombinant Protein Producing Komagataella phaffii

ABSTRACT The yeast Komagataella phaffii (syn. Pichia pastoris) is a highly effective and well‐established host for the production of recombinant proteins. The redox balance of its secretory pathway, which is multi‐organelle dependent, is of high importance for producing secretory proteins. Redox imb...

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Auteurs principaux:	Aliki Kostopoulou, Corinna Rebnegger, Borja Ferrero‐Bordera, Matthias Mattanovich, Sandra Maaß, Dörte Becher, Brigitte Gasser, Diethard Mattanovich
Format:	Artigo
Langue:	Inglês
Publié:	Wiley 2025-02-01
Collection:	Microbial Biotechnology
Sujets:	chemostat cultivation glutathione redox potential hypoxia Komagataella phaffii yeast
Accès en ligne:	https://doi.org/10.1111/1751-7915.70106
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