Ciliary p75 neurotrophin receptor (p75NTR) facilitates the enrichment of exogenous amyloid beta (Aβ 1–42) peptide and promotes oxidative stress in human hippocampal astrocytes

Abstract Accumulation of amyloid beta 1–42 (Aβ42) peptide in the extracellular space in the brain is a major observation in Alzheimer’s Disease (AD)-related pathology. Astrocytes are known to play pivotal role in clearing the extracellular aβ peptide from the brain, and the underlying mechanism of A...

詳細記述

書誌詳細

主要な著者:	Ankan Gupta, Karthikeyan Thirugnanam, Zachary Bice, Allison K. Lowman, Kevin R. Rarick, Peter S. LaViolette, Amy Pan, Malgorzata Franczak, Ramani Ramchandran
フォーマット:	Artigo
言語:	Inglês
出版事項:	BMC 2026-03-01
シリーズ:	BMC Molecular and Cell Biology
主題:	Hippocampus Dementia Alzheimer disease Reactive oxygen species Oxidative stress Cell cycle
オンライン･アクセス:	https://doi.org/10.1186/s12860-026-00581-z
タグ:	タグ追加 タグなし, このレコードへの初めてのタグを付けませんか!