Application of the estimand framework for an emulated trial using reference based multiple imputation to investigate informative censoring
Abstract Background The ICH E9 (R1) addendum on Estimands and Sensitivity analysis in Clinical trials proposes a framework for the design and analysis of clinical trials aimed at improving clarity around the definition of the targeted treatment effect (the estimand) of a study. Methods We adopt the...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BMC
2024-10-01
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| Col·lecció: | BMC Medical Research Methodology |
| Matèries: | |
| Accés en línia: | https://doi.org/10.1186/s12874-024-02364-6 |
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