The Sin3A/MAD1 Complex, through Its PAH2 Domain, Acts as a Second Repressor of Retinoic Acid Receptor Beta Expression in Breast Cancer Cells

Retinoids are essential in balancing proliferation, differentiation and apoptosis, and they exert their effects through retinoic acid receptors (RARs) and retinoid X receptors (RXRs). RARβ is a tumor-suppressor gene silenced by epigenetic mechanisms such as DNA methylation in breast, cervical and no...

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Hlavní autoři:	Nisha Rani Dahiya, Boris A. Leibovitch, Rama Kadamb, Nidhi Bansal, Samuel Waxman
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2022-03-01
Edice:	Cells
Témata:	breast cancer E-box HDAC: histone deacetylases MAD1: MAX dimerization protein NCoR: nuclear receptor corepressor 1 PAH: paired amphipathic domains
On-line přístup:	https://www.mdpi.com/2073-4409/11/7/1179
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