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Accumulation of mitochondrial DNA with a point mutation in tRNALeu(UUR) gene induces brain dysfunction in mice

Brain functions are mediated via the complex interplay between several complex factors, and hence, identifying the underlying cause of an abnormality within a certain brain region can be challenging. In mitochondrial disease, abnormalities in brain function are thought to be attributed to accumulati...

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Principais autores: Kaori Ishikawa, Daiki Miyata, Satoko Hattori, Haruna Tani, Takayoshi Kuriyama, Fan-Yan Wei, Tsuyoshi Miyakawa, Kazuto Nakada
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2024-10-01
coleção:Pharmacological Research
Assuntos:
Mitochondrial DNA
Brain dysfunction
MtDNA tRNALeu(UUR)
Prepulse inhibition
Environmental factors
Memory
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S1043661824003190
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