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Effects of Specific Endothelin-1 Receptor Antagonists on Proliferation and Fibronectin Production of Glomerular Mesangial Cells Stimulated with Angiotensin II

Angiotensin II (Ang-II) is a potent vasoactive hormone, which plays an important role in the pathogenesis of glomerulosclerosis. Ang-II activates many cytokine systems in the kidney. Recent studies indicate that Ang-II is closely related to the activation of the endothelin-1 (ET-1) system. The prese...

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Autors principals: Hung-Tien Kuo, Mei-Chuan Kuo, Hung-Chun Chen
Format: Artigo
Idioma:Inglês
Publicat: Wiley 2006-08-01
Col·lecció:Kaohsiung Journal of Medical Sciences
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Accés en línia:http://www.sciencedirect.com/science/article/pii/S1607551X09703250
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