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Metabolic constraints drive self-organization of specialized cell groups

How phenotypically distinct states in isogenic cell populations appear and stably co-exist remains unresolved. We find that within a mature, clonal yeast colony developing in low glucose, cells arrange into metabolically disparate cell groups. Using this system, we model and experimentally identify...

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Principais autores: Sriram Varahan, Adhish Walvekar, Vaibhhav Sinha, Sandeep Krishna, Sunil Laxman
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications Ltd 2019-06-01
Serija:eLife
Teme:
Online dostop:https://elifesciences.org/articles/46735
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