Metabolic constraints drive self-organization of specialized cell groups

How phenotypically distinct states in isogenic cell populations appear and stably co-exist remains unresolved. We find that within a mature, clonal yeast colony developing in low glucose, cells arrange into metabolically disparate cell groups. Using this system, we model and experimentally identify...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Sriram Varahan, Adhish Walvekar, Vaibhhav Sinha, Sandeep Krishna, Sunil Laxman
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	eLife Sciences Publications Ltd 2019-06-01
Цуврал:	eLife
Нөхцлүүд:	self-organization cell states trehalose yeast pentose phosphate pathway gluconeogenesis
Онлайн хандалт:	https://elifesciences.org/articles/46735
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!