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New Era of Mapping and Understanding Common Fragile Sites: An Updated Review on Origin of Chromosome Fragility

Common fragile sites (CFSs) are specific genomic loci prone to forming gaps or breakages upon replication perturbation, which correlate well with chromosomal rearrangement and copy number variation. CFSs have been actively studied due to their important pathophysiological relevance in different dise...

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Bibliografische gegevens
Hoofdauteurs: Fang Ji, Xinli Zhu, Hongwei Liao, Liujian Ouyang, Yingfei Huang, Madiha Zahra Syeda, Songmin Ying
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2022-05-01
Reeks:Frontiers in Genetics
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Online toegang:https://www.frontiersin.org/articles/10.3389/fgene.2022.906957/full
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