Substrate-bound CCL21 and ICAM1 combined with soluble IL-6 collectively augment the expansion of antigen-specific murine CD4+ T cells

Abstract: Immune processes within the complex microenvironment of the lymph node involve multiple intercellular, cell-matrix, and paracrine interactions, resulting in the expansion of antigen-specific T cells. Inspired by the lymph node microenvironment, we aimed to develop an ex vivo “synthetic imm...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Shimrit Adutler-Lieber, Irina Zaretsky, Helena Sabany, Elena Kartvelishvily, Ofra Golani, Benjamin Geiger, Nir Friedman
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2017-06-01
Schriftenreihe:	Blood Advances
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S2473952920302159
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!