PARP1 inhibition protects mice against Japanese encephalitis virus infection

Summary: Japanese encephalitis (JE) is a vector-borne viral disease that causes acute encephalitis in children. Although vaccines have been developed against the JE virus (JEV), no effective antiviral therapy exists. Our study shows that inhibition of poly(ADP-ribose) polymerase 1 (PARP1), an NAD+-d...

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Principais autores:	Perumal Arumugam Desingu, Sneha Mishra, Lavanya Dindi, Shalini Srinivasan, Raju S. Rajmani, Venkatraman Ravi, Ankit Kumar Tamta, Sukanya Raghu, Krishnega Murugasamy, Anwit Shriniwas Pandit, Nagalingam R. Sundaresan
格式:	Artigo
語言:	Inglês
出版:	Elsevier 2023-09-01
叢編:	Cell Reports
主題:	CP: Microbiology
在線閱讀:	http://www.sciencedirect.com/science/article/pii/S2211124723011142
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