Tribbles Pseudokinase 3 Converts Sorafenib Therapy to Neutrophil‐Mediated Lung Metastasis in Hepatocellular Carcinoma

Abstract Rapid development of resistance to sorafenib and subsequent hyperprogression in patients with advanced hepatocellular carcinoma (HCC) pose significant challenges, with the underlying mechanisms still largely unknown. Herein, sorafenib‐induced TRIB3 is identified as a liver‐specific determin...

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Autori principali:	Xu‐Yan Wang, Yuan Liao, Rui‐Qi Wang, Yi‐Tong Lu, Ying‐Zhe Wang, Yu‐Qi Xin, Dong‐Ming Kuang, Xiang‐Ming Lao, Junying Xu, Zhi‐Ling Zhou, Kunhua Hu
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Wiley 2025-04-01
Serie:	Advanced Science
Soggetti:	hepatocellular carcinoma lung metastasis neutrophil sorafenib resistance TRIB3
Accesso online:	https://doi.org/10.1002/advs.202413682
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