TRAF5 is a downstream target of MAVS in antiviral innate immune signaling.
The recognition of nucleic acids by the innate immune system during viral infection results in the production of type I interferons and the activation of antiviral immune responses. The RNA helicases RIG-I and MDA-5 recognize distinct types of cytosolic RNA species and signal through the mitochondri...
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| Главные авторы: | , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science (PLoS)
2010-02-01
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| Серии: | PLoS ONE |
| Online-ссылка: | http://europepmc.org/articles/PMC2820086?pdf=render |
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