Targeting SARS-CoV-2 programmed −1 ribosomal frameshifting: structural dynamics and RNA-directed antiviral strategies

ABSTRACT Programmed −1 ribosomal frameshifting (−1 PRF) is a translational recoding mechanism used by many RNA viruses to regulate the expression of viral replication proteins. In coronaviruses, including SARS-CoV-2, −1 PRF is controlled by a conserved frameshift stimulation element containing a thr...

पूर्ण विवरण

ग्रंथसूची विवरण

मुख्य लेखकों:	Neha Jeena, Inshad Ali Khan
स्वरूप:	Artigo
भाषा:	Inglês
प्रकाशित:	ASM 2026-09-01
श्रृंखला:	Antimicrobial Agents and Chemotherapy
विषय:	programmed −1 ribosomal frameshifting SARS-CoV-2 RNA pseudoknot RNA-targeted therapeutics conformational dynamics
ऑनलाइन पहुंच:	https://journals.asm.org/doi/10.1128/aac.00687-26
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