Stress increases blood beta‐hydroxybutyrate levels and prefrontal cortex NLRP3 activity jointly in a rodent model

Abstract Aim This study aimed to assess the response of endogenous beta‐hydroxybutyrate to psychological stress, and its association with nucleotide‐binding domain, leucine‐rich repeat, pyrin domain‐containing 3 (NLRP3) inflammasome, and stress‐induced behavior. Methods Male C57BL/6J mice were subje...

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Autori principali:	Tsuyoshi Nishiguchi, Masaaki Iwata, Naofumi Kajitani, Akihiko Miura, Ryoichi Matsuo, Shumei Murakami, Yumeto Nakada, Shenghong Pu, Yuki Shimizu, Tatsuya Tsubakino, Takehiko Yamanashi, Gen Shinozaki, Jun Tsubota, Yukihiko Shirayama, Ken Watanabe, Koichi Kaneko
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Wiley 2021-06-01
Serie:	Neuropsychopharmacology Reports
Soggetti:	beta‐hydroxybutyrate (BHB) depression inflammasomes leucine‐rich repeat nucleotide‐binding domain prefrontal cortex
Accesso online:	https://doi.org/10.1002/npr2.12164
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