Synthesis and Evaluation of Thiol-Conjugated Poloxamer and Its Pharmaceutical Applications

The current study was designed to convert the poloxamer (PLX) into thiolated poloxamer (TPLX), followed by its physicochemical, biocompatibilities studies, and applications as a pharmaceutical excipient in the development of tacrolimus (TCM)-containing compressed tablets. Thiolation was accomplished...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής

Κύριοι συγγραφείς:	Muhammad Zaman, Sadaf Saeed, Rabia Imtiaz Bajwa, Muhammad Shafeeq Ur Rahman, Saeed Ur Rahman, Muhammad Jamshaid, Muhammad F. Rasool, Abdul Majeed, Imran Imran, Faleh Alqahtani, Sultan Alshehri, Abdullah F. AlAsmari, Nemat Ali, Mohammed S. Alasmari
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	MDPI AG 2021-05-01
Σειρά:	Pharmaceutics
Θέματα:	poloxamer thiourea thiolation mucoadhesion drug release in vivo analysis
Διαθέσιμο Online:	https://www.mdpi.com/1999-4923/13/5/693
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