Synthesis and Evaluation of Thiol-Conjugated Poloxamer and Its Pharmaceutical Applications

The current study was designed to convert the poloxamer (PLX) into thiolated poloxamer (TPLX), followed by its physicochemical, biocompatibilities studies, and applications as a pharmaceutical excipient in the development of tacrolimus (TCM)-containing compressed tablets. Thiolation was accomplished...

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Detalles Bibliográficos

Principais autores:	Muhammad Zaman, Sadaf Saeed, Rabia Imtiaz Bajwa, Muhammad Shafeeq Ur Rahman, Saeed Ur Rahman, Muhammad Jamshaid, Muhammad F. Rasool, Abdul Majeed, Imran Imran, Faleh Alqahtani, Sultan Alshehri, Abdullah F. AlAsmari, Nemat Ali, Mohammed S. Alasmari
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2021-05-01
Series:	Pharmaceutics
Assuntos:	poloxamer thiourea thiolation mucoadhesion drug release in vivo analysis
Acceso en liña:	https://www.mdpi.com/1999-4923/13/5/693
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