Integrative Genome-Scale DNA Methylation Analysis of a Large and Unselected Cohort Reveals 5 Distinct Subtypes of Colorectal AdenocarcinomasSummary

Background & Aims: Colorectal cancer is an epigenetically heterogeneous disease, however, the extent and spectrum of the CpG island methylator phenotype (CIMP) is not clear. Methods: Genome-scale methylation and transcript expression were measured by DNA Methylation and RNA expression microarray in...

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Détails bibliographiques

Auteurs principaux:	Lochlan Fennell, Troy Dumenil, Leesa Wockner, Gunter Hartel, Katia Nones, Catherine Bond, Jennifer Borowsky, Cheng Liu, Diane McKeone, Lisa Bowdler, Grant Montgomery, Kerenaftali Klein, Isabell Hoffmann, Ann-Marie Patch, Stephen Kazakoff, John Pearson, Nicola Waddell, Pratyaksha Wirapati, Paul Lochhead, Yu Imamura, Shuji Ogino, Renfu Shao, Sabine Tejpar, Barbara Leggett, Vicki Whitehall
Format:	Artigo
Langue:	Inglês
Publié:	Elsevier 2019-01-01
Collection:	Cellular and Molecular Gastroenterology and Hepatology
Accès en ligne:	http://www.sciencedirect.com/science/article/pii/S2352345X19300414
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