PIAS1 potentiates the anti-EBV activity of SAMHD1 through SUMOylation
Abstract Background Sterile alpha motif and HD domain 1 (SAMHD1) is a deoxynucleotide triphosphohydrolase (dNTPase) that restricts the infection of a variety of RNA and DNA viruses, including herpesviruses. The anti-viral function of SAMHD1 is associated with its dNTPase activity, which is regulated...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
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BMC
2021-07-01
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| Schriftenreihe: | Cell & Bioscience |
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| Online-Zugang: | https://doi.org/10.1186/s13578-021-00636-y |
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