PIAS1 potentiates the anti-EBV activity of SAMHD1 through SUMOylation
Abstract Background Sterile alpha motif and HD domain 1 (SAMHD1) is a deoxynucleotide triphosphohydrolase (dNTPase) that restricts the infection of a variety of RNA and DNA viruses, including herpesviruses. The anti-viral function of SAMHD1 is associated with its dNTPase activity, which is regulated...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
BMC
2021-07-01
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| Colección: | Cell & Bioscience |
| Materias: | |
| Acceso en línea: | https://doi.org/10.1186/s13578-021-00636-y |
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