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Campylobacter jejuni Cytolethal Distending Toxin Induces GSDME-Dependent Pyroptosis in Colonic Epithelial Cells

BackgroundCytolethal distending toxin (CDT) is a critical virulence factor of Campylobacter jejuni, and it induces cell death and regulates inflammation response in human epithelial cells. Pyroptosis is an inflammatory form of programmed cell death (PCD), but whether it is involved in CDT-mediated c...

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Principais autores: Jiayun Gu, Yan Lin, Zhichao Wang, Qicong Pan, Guohua Cai, Qigai He, Xiaojuan Xu, Xuwang Cai
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2022-04-01
Serija:Frontiers in Cellular and Infection Microbiology
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Online dostop:https://www.frontiersin.org/articles/10.3389/fcimb.2022.853204/full
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