Revisiting bacterial cytolethal distending toxin structure and function

Cytolethal distending toxins (CDTs) are intracellular-acting bacterial genotoxins generated by a diverse group of mucocutaneous human pathogens. CDTs must successfully bind to the plasma membrane of host cells in order to exert their modulatory effects. Maximal toxin activity requires all three toxi...

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Bibliografiska uppgifter

Huvudupphov:	Henry Chen, Claire J. Ang, Molly K. Crowder, William M. Brieher, Steven R. Blanke
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	Frontiers Media S.A. 2023-11-01
Serie:	Frontiers in Cellular and Infection Microbiology
Ämnen:	AB toxin cytolethal distending toxin protein-protein interactions Campylobacter jejuni DNA damage holotoxin structure
Länkar:	https://www.frontiersin.org/articles/10.3389/fcimb.2023.1289359/full
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