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Kinetic competition during the transcription cycle results in stochastic RNA processing

Synthesis of mRNA in eukaryotes involves the coordinated action of many enzymatic processes, including initiation, elongation, splicing, and cleavage. Kinetic competition between these processes has been proposed to determine RNA fate, yet such coupling has never been observed in vivo on single tran...

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Bibliografische Detailangaben
Hauptverfasser: Antoine Coulon, Matthew L Ferguson, Valeria de Turris, Murali Palangat, Carson C Chow, Daniel R Larson
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications Ltd 2014-10-01
Schriftenreihe:eLife
Schlagworte:
Online-Zugang:https://elifesciences.org/articles/03939
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