Kinetic competition during the transcription cycle results in stochastic RNA processing

Synthesis of mRNA in eukaryotes involves the coordinated action of many enzymatic processes, including initiation, elongation, splicing, and cleavage. Kinetic competition between these processes has been proposed to determine RNA fate, yet such coupling has never been observed in vivo on single tran...

وصف كامل

التفاصيل البيبلوغرافية

المؤلفون الرئيسيون:	Antoine Coulon, Matthew L Ferguson, Valeria de Turris, Murali Palangat, Carson C Chow, Daniel R Larson
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	eLife Sciences Publications Ltd 2014-10-01
سلاسل:	eLife
الموضوعات:	transcription RNA processing splicing single-molecule imaging fluctuation analysis
الوصول للمادة أونلاين:	https://elifesciences.org/articles/03939
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!