Decorin blocks scarring and cystic cavitation in acute and induces scar dissolution in chronic spinal cord wounds

In the injured central nervous system (CNS), transforming growth factor (TGF)-β1/2-induced scarring and wound cavitation impede axon regeneration implying that a combination of both scar suppression and axogenic treatments is required to achieve functional recovery. After treating acute and chronic...

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Detalhes bibliográficos

Principais autores:	Zubair Ahmed, Daljeet Bansal, Katie Tizzard, Sarina Surey, Maryam Esmaeili, Ana Maria Gonzalez, Martin Berry, Ann Logan
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2014-04-01
coleção:	Neurobiology of Disease
Assuntos:	Spinal cord injury Decorin ECM Scarring MMP TIMP
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S0969996113003525
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