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The neuroregenerative effects of topical decorin on the injured mouse cornea

Abstract Background The cornea is innervated with a rich supply of sensory nerves that play important roles in ocular surface health. Any injury or pathology of the corneal nerves increases the risk of dry eye disease and infection. This study aims to evaluate the therapeutic potential of topical de...

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Principais autores: Mengliang Wu, Laura E. Downie, Liam M. Grover, Richard J. A. Moakes, Saaeha Rauz, Ann Logan, Haihan Jiao, Lisa J. Hill, Holly R. Chinnery
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2020-05-01
Serier:Journal of Neuroinflammation
Fag:
Corneal sensory nerves
Nerve regeneration
Decorin
Dendritic cells
Macrophages
Immunomodulation
Online adgang:http://link.springer.com/article/10.1186/s12974-020-01812-6
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