Mitochondrial inorganic polyphosphate is required to maintain proteostasis within the organelle

The existing literature points towards the presence of robust mitochondrial mechanisms aimed at mitigating protein dyshomeostasis within the organelle. However, the precise molecular composition of these mechanisms remains unclear. Our data show that inorganic polyphosphate (polyP), a polymer well-c...

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Autores principales:	Renata T. Da Costa, Pedro Urquiza, Matheus M. Perez, YunGuang Du, Mei Li Khong, Haiyan Zheng, Mariona Guitart-Mampel, Pia A. Elustondo, Ernest R. Scoma, Vedangi Hambardikar, Beatrix Ueberheide, Julian A. Tanner, Alejandro Cohen, Evgeny V. Pavlov, Cole M. Haynes, Maria E. Solesio
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Frontiers Media S.A. 2024-07-01
Colección:	Frontiers in Cell and Developmental Biology
Materias:	mitochondria mitochondrial inorganic polyphosphate polyP protein homeostasis proteostasis
Acceso en línea:	https://www.frontiersin.org/articles/10.3389/fcell.2024.1423208/full
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