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Mitochondrial inorganic polyphosphate is required to maintain proteostasis within the organelle

The existing literature points towards the presence of robust mitochondrial mechanisms aimed at mitigating protein dyshomeostasis within the organelle. However, the precise molecular composition of these mechanisms remains unclear. Our data show that inorganic polyphosphate (polyP), a polymer well-c...

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Principais autores: Renata T. Da Costa, Pedro Urquiza, Matheus M. Perez, YunGuang Du, Mei Li Khong, Haiyan Zheng, Mariona Guitart-Mampel, Pia A. Elustondo, Ernest R. Scoma, Vedangi Hambardikar, Beatrix Ueberheide, Julian A. Tanner, Alejandro Cohen, Evgeny V. Pavlov, Cole M. Haynes, Maria E. Solesio
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2024-07-01
叢編:Frontiers in Cell and Developmental Biology
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在線閱讀:https://www.frontiersin.org/articles/10.3389/fcell.2024.1423208/full
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