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A Novel Prognostic Signature Based on Glioma Essential Ferroptosis-Related Genes Predicts Clinical Outcomes and Indicates Treatment in Glioma

BackgroundFerroptosis is a form of programmed cell death (PCD) that has been implicated in cancer progression, although the specific mechanism is not known. Here, we used the latest DepMap release CRISPR data to identify the essential ferroptosis-related genes (FRGs) in glioma and their role in pati...

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Principais autores: Debo Yun, Xuya Wang, Wenbo Wang, Xiao Ren, Jiabo Li, Xisen Wang, Jianshen Liang, Jie Liu, Jikang Fan, Xiude Ren, Hao Zhang, Guanjie Shang, Jingzhang Sun, Lei Chen, Tao Li, Chen Zhang, Shengping Yu, Xuejun Yang
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2022-06-01
Serier:Frontiers in Oncology
Fag:
glioma
ferroptosis
cancer essential genes
LASSO analysis
risk model
clinical outcomes
Online adgang:https://www.frontiersin.org/articles/10.3389/fonc.2022.897702/full
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