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Cytomegalovirus infection impairs immune responses and accentuates T-cell pool changes observed in mice with aging.

Prominent immune alterations associated with aging include the loss of naïve T-cell numbers, diversity and function. While genetic contributors and mechanistic details in the aging process have been addressed in multiple studies, the role of environmental agents in immune aging remains incompletely...

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Autors principals: Luka Cicin-Sain, James D Brien, Jennifer L Uhrlaub, Anja Drabig, Thomas F Marandu, Janko Nikolich-Zugich
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2012-01-01
Col·lecció:PLoS Pathogens
Accés en línia:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1002849&type=printable
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