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TF Profiler: a transcription factor inference method that broadly measures transcription factor activity and identifies mechanistically distinct networks

Abstract TF Profiler is a method of inferring transcription factor (TF) regulatory activity, i.e., when a TF is present and actively participating in the regulation of transcription, directly from nascent sequencing assays such as PRO-seq and GRO-seq. While ChIP assays have measured DNA localization...

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Váldodahkkit: Taylor Jones, Rutendo F. Sigauke, Lynn Sanford, Dylan J. Taatjes, Mary A. Allen, Robin D. Dowell
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: BMC 2025-04-01
Ráidu:Genome Biology
Fáttát:
Liŋkkat:https://doi.org/10.1186/s13059-025-03545-2
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