25-Hydroxycholesterol Inhibits Kaposi’s Sarcoma Herpesvirus and Epstein-Barr Virus Infections and Activates Inflammatory Cytokine Responses

ABSTRACT Oncogenic gammaherpesviruses express viral products during latent and lytic infection that block the innate immune response. Previously, we found that Kaposi’s sarcoma herpesvirus (KSHV/human herpesvirus-8) viral microRNAs (miRNAs) downregulate cholesterol biogenesis, and we hypothesized th...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Anna K. P. Serquiña, Takanobu Tagawa, Daniel Oh, Guruswamy Mahesh, Joseph M. Ziegelbauer
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology 2021-12-01
Schriftenreihe:	mBio
Schlagworte:	EBV KSHV cholesterol innate immunity
Online-Zugang:	https://journals.asm.org/doi/10.1128/mBio.02907-21
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!