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25-Hydroxycholesterol Inhibits Kaposi’s Sarcoma Herpesvirus and Epstein-Barr Virus Infections and Activates Inflammatory Cytokine Responses

ABSTRACT Oncogenic gammaherpesviruses express viral products during latent and lytic infection that block the innate immune response. Previously, we found that Kaposi’s sarcoma herpesvirus (KSHV/human herpesvirus-8) viral microRNAs (miRNAs) downregulate cholesterol biogenesis, and we hypothesized th...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Anna K. P. Serquiña, Takanobu Tagawa, Daniel Oh, Guruswamy Mahesh, Joseph M. Ziegelbauer
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2021-12-01
Saila:mBio
Gaiak:
Sarrera elektronikoa:https://journals.asm.org/doi/10.1128/mBio.02907-21
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