Mindin-mediated αM-integrin endocytosis activates STAT3 to maintain keratinocyte stemness

Abstract Background Keratinocyte stem cells are essential for maintaining epidermal homeostasis and enabling efficient tissue repair. Regulation of their self-renewal and differentiation is critical, as its disruption can impair regeneration and drive pathological conditions such as chronic wounds a...

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Autori principali:	Binita Dam, Johan Ajnabi, Tirthankar Saha, Ashish Shrivastava, Krithika Badarinath, Akshay Hegde, Abhik Dutta, Siddham Jasoria, Sunny Kataria, Ashutosh Singh, Colin Jamora
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2026-06-01
Serie:	Cell Communication and Signaling
Soggetti:	F-Spondin αMβ2 endocytosis STAT3 activation Endosomal acidification Keratinocyte stemness
Accesso online:	https://doi.org/10.1186/s12964-026-02970-5
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